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MagnetoReduction Assays
MRA offers two types of instruments for assays:
1) electronic assay (MRA-E), and
2) superconductive assay (MRA-S)
This affords a high-sensitivity, wash-free, easy-operation, color-independence, and on-site-test platform for quantitatively assaying proteins, bacteria, viruses, and other biomolecules in humans, agricultural, aquatic and animal products.
The advantages of MRA are pointed out via comparing its performances with those of popularly used technologies, such as sandwich-ELISA (ELISA-S), competitive-ELISA (ELISA-C), HPLC, and LC/MS/MS.
| Item/Assay | MRA- E | MRA- S | ELISA-S | ELISA- C | HPLC | LC/MS/MS |
| Antibody | Y-single | Y- single | Y- two | Y- two | Y-single | N |
| Direct Assay | Y | Y | N | N | Y | N |
| Homog. Assay | Y | Y | N | N | Y | Y |
| Wash Step | N | N | Y | Y | N | N |
| Sample Color Dependence | N | N | Y | Y | Y | N |
| Sample Pre-purification | N | N | N | N | N | Y |
| Operation | Easy | Easy | Not Easy | Not Easy | Difficult | Very Difficult |
| Small molecules | Y | Y | N | Y | Y | y |
| On-site assay | Y | N | N | N | N | N |
| Mobility | High | Medium | Medium | Medium | Low | Very Low |
| Positive control | N | N | Y | Y | Y | Y |
| Sensitivity | 10ppt | 10E4ppt | 0.1ppb | 0.1ppb | 0.1ppb | 1ppt |
| Price (US$) | 35,000 | 35,000 | 20,000 | 300,000 |
| Code | Description | Sensitivity |
| MRA-01 | MRA (electronic assay) | <0.1ppm |
| MRA-02 | MRA (superconductive assay) | 1ppt |
