IGFBP-1 EIA (Insulin-like growth factor binding protein-1) determines IGFBP-1 concentration in human serum, amniotic fluid and plasma. IGFBP-1 concentration is an indicator for insulin production of beta-cells and can be used for evaluation of nutritional status.
Product Attributes
No cross reaktivity to IGFBP-2, IGFBP-4, IGFBP-5 or IGFBP-6
Inter- and Intraassayvariance << 7%
Recovery in human serum: 100%
IGFBP-2 EIA
IGFBP-2 EIA (Insulin-like Growth Factor Binding Protein 2) detects human IGFBP-2 concentration in serum, cell culture supernatants, breast milk and cerebrospinal fluid. Concentration of IGFBP-2 is elevated in several malignant diseases as liver carcinoma, prostate cancer and brain tumor so IGFBP-2 is a possible marker for tumor growth.
Product Attributes
Reference values for healthy humans of a broad range of age
Sensitivity of 0.2 ng/ml
Inter-and Intraasaayvariance< 10%
Recovery in human serum 97 - 115%
IGFBP-3 EIA
The IGFBP-3 EIA (Insulin-like bindingprotein -3) is very well suited for determination of IGFBP-3 concentration in human serum and plasma. Also IGFBP-3 content of other body fluids and cell culture supernatants can be measured.
IGFBP-3 is the one of the key parameters in diagnosis of growth failure. Specially in babies/children the diagnostic value of IGFBP-3 concentration is superior to IGF-I measurement.
Assay characteristics
only small sample volumes necessary, ideal for pediatrician
low variance: 6.3% inter-assay and 4.5% intra-assay variation