Magnetic Beads (MB) Conjugated with Antibodies to Infectious Diseases (AB-MB)
Magnetic separation technology, using magnetic particles, is quick and easy method for sensitive and reliable capture of specific proteins, genetic material and other biomolecules. The technique offers an advantage in terms of subjecting the analyte to very little mechanical stress compared to other methods. Secondly, these methods are non-laborious, cheap and often highly scalable. Moreover, techniques employing magnetism are more amenable to automation and miniaturization.
Immunomagnetic separation is used extensively for detection of pathogenic bacteria and virus in clinical, food and environmental samples. Immunomagnetic assays are becoming an important tool in clinical diagnostics and in fundamental investigations, because of its sensitivity, specificity and general applicability. Magnetic particles have been applied increasingly for various immunoassays that include fluoroimmunoassays, enzyme immunoassays or radioimmunoassays.
Magnetic particles bound with primary or secondary antibodies are used for separation and quantification of diverse antigens. Use of magnetically bound antibodies eliminates the centrifugation step thus reducing assay time and simplifying operation thereby increasing the efficiency and accuracy of the assay.