CD4 Cell Separation

Description

CD4 is an accessory molecule. This antigen binds to MHC class II molecules and is a co-receptor in MHC class II restricted antigen-induced activation. CD4 is expressed on T helper cells and at a lower level on thymocytes and monocytes. The CD4 molecule is a receptor for the HIV-1 envelope protein gp120 and plays an important role in the aggressive infection process

Cell-beads are superparamagnetic nanoparticles optimized for the positive selection and depletion of cells using commercially available separation columns. These cell-beads are designed for direct labeling of cells. A specific polymer on the surface of the beads were developed and selected highly specific antibodies, thus reducing non specific capture and optimizing the separation. The small size combined to the specific polymer allows the cells to be further evaluated in downstream application like flow cytometry or functional studies such as proliferation or cytotoxicity assay.

Benefits

Effective: optimal purity and recovery

Convenient: suitable with current column based system

Compatible with a direct analysis in flow cytometry

Gentle cell separation system: cell integrity is conserved

Typical results:

Specifications

The Kit contains all of the components required for 100 millions total cells separation.

Product Code

	Code	Product Description	Capacity
	CSB-001	Beads for CD4 cell separation	100 millions cells
	CSB-002	Beads for CD8 cell separation	100 millions cells
	CSB-003	Beads for CD14 cell separation	100 millions cells